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Protein Principles for Diabetes



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By : Jim Duffy    29 or more times read
Submitted 2010-04-14 15:05:11
Dietary considerations will frequently present a difficult dilemma for diabetes sufferers. Although the intake may be nutritious, metabolizing it can be an entirely different matter. Additionally there is the issue of progression of diabetic troubles when one winds up with surplus glucose or fat in the system. Excess carbohydrates in a meal , and therefore the resulting unrestrained blood sugar levels can be harmful to any number of tissues, from the lens of the eye, to the neurons, small blood vessels and also the kidneys and liver. Fat is additionally a drawback with greater incidences of atherosclerosis, large vessel disease and kidneys problems. What determines the suitable macronutrient for the people with diabetes? More than enough medical research exists to recommend that in people suffering from diabetes, proteins are probably the most effective bet.

Proteins are the usual selection of the body when it's faced with diabetes. The body of somebody with uncontrolled diabetes converts muscle protein into amino acids which then the liver uses to make glucose for the body. If untreated this can produce a commotion within the body. As proteins have to provide enough energy to substitute for carbohydrates, proteins are broken down much quicker than they're created. The body ends up with a protein deficit, a situation with subtle, yet far-reaching effects on routine body functions. Significantly, for people suffering from diabetes, a protein deficit has been proven to weaken the body's resistance to infections (Ganong WF). Replenishing the depleting protein stores may be a important demand of all diabetic diets.

There is a considerable amount of literature that documents the effects of proteins in a diabetic diet. The American Association of Clinical Endocrinologists have made it clear that not much evidence exists toshow that those who are afflicted with diabetes have to reduce their intake of dietary proteins. The AACE recommends that 10-20% of the caloric intake in people suffering from diabetes should come from proteins (AACE Diabetes Guidelines). In fact, it is believed that this can be one nutrient that does not increase blood glucose levels in both diabetics and healthy subjects (Gannon et al).

Nutrition therapy for diabetes has progressed from prevention of obesity or weight gain to improving insulin’s effectiveness and contributing to improved metabolic management (Franz MJ). In this new role, a high protein diet 30% of total food energy forms a terribly pertinent part of nutrition therapy. One of the foremost necessary causes for type II diabetes is obesity. Excess body fat raises insulin resistance and higher levels of insulin are needed to bring down blood sugars as the weight increases (Ganong WF). Another problem with excess fat is the clogging of arteries with atherosclerotic plaques that's responsible for a large number of diabetic problems. Any mechanism that reduces body fat decreases insulin resistance and improves blood glucose control. Parker et al have also shown that a high protein diet decreased abdominal and total fat mass in ladies with type II diabetes. Other studies by Gannon et al. and Nuttall et al have also proven that blood glucose levels and glycosylated hemoglobin (a marker of long term diabetic management) reduce after 5 weeks on a diet containing 30% of the entire food energy in the shape of proteins and low carbohydrate content. It is assumed that a high protein diet has a favorable effect in diabetes thanks to the flexibility of proteins and amino acids to stimulate insulin release from the pancreas. So, a high protein diet isn't only safe in diabetes, but can also be beneficial, resulting in improved glycemic control, and decreased risk of complications related to diabetes.

The benefits of a high protein diet program don't end there. Individual protein components of such a diet, if fittingly chosen, will have alternative benefits as well. Dietary supplements containing proteins like whey and casein come favorably suggested. Casein is a milk protein and has the ability to create a gel or clot in the stomach. The power to create this clot makes it very efficient in nutrient supply. The clot is able to provide a constant, slow release of amino acids into the blood stream, typically lasting for several hours (Boirie et al. 1997). A gradual continued release of nutrients goes well with the limited amount of insulin that may be created by the pancreas in diabetic patients. A protein shot that has casein can consequently increase the amount of energy assimilated from each meal and, at the same time, lessen the necessity for medicinal interventions to manage blood sugar.

Whey proteins and caseins additionally both contain “casokinins” and “lactokinins’, (FitzGerald) which have been known to lessen both systolic and diastolic blood pressure in hypertensive people (Seppo). In addition whey protein creates bioactive amine within the gut which promotes immunity. Whey protein has a plentiful amount of the amino acid cysteine. Cysteine seems to boost glutathione levels, which has been shown to have robust antioxidant characteristics -- antioxidants mop up free radicals that generate cell death and have a large part to play in the aging process.

Thus, development of a protein shooter containing casein and whey will offer an suitable high protein diet and its nutrition related benefits to those suffering from diabetes, obesity and hypercholesterolemia.


REFERENCES

The American Association of Clinical Endocrinologists. Medical guidelines for the management of diabetes. AACE Diabetes Guidelines, Endocr Pract. 2002; 8(Suppl 1).

Boirie, Y., Dangin, M., Gachon, P., Vasson, M.P., Maubois, J.L. and Beaufrere, B. (1997) Slow and fast dietary proteins differently modulate postprandial protein accretion. Proclamations of National Academy of Sciences 94, 14930-14935.

Counous, G. Whey protein concentrates (WPC) and glutathione modulation in cancer treatment. Anticancer Research 2000; 20, 4785-4792

FitzGerald RJ, Murray BA, Walsh D J. Hypotensive Peptides from Milk Proteins. J. Nutr. 134: 980S–988S, 2004.

Franz MJ. Prioritizing diabetes nutrition recommendations based on evidence. Minerva Med. 2004; 95(2):115-23.

Gannon et al An increase in dietary protein improves the blood glucose response in persons with type 2 diabetes. Am J Clin Nutr 2003; 78:734– 41.

Gannon MC, Nuttall J A, Damberg G. Effect of protein ingestion on the glucose appearance rate in people with type II diabetes. J Clin Endocrinol Metab 86: 1040–1047, 2001

Ganong W F. Review of Medical Physiology, 21st Ed. Lange Publications 2003

Ha, E. and Zemel, M.B. Functional properties of whey, whey components, and essential amino acids: mechanisms underlying health benefits for active people. Journal of Nutritional Biochemistry 2003; 14, 251-258.

Kent KD, Harper WJ, Bomser JA. Effect of whey protein isolate on intracellular glutathione and oxidant-induced cell death in human prostate epithelial cells. Toxicol in Vitro. 2003; 17(1):27-33.

Nuttall et al. The Metabolic Response of Subjects with Type II Diabetes to a High-Protein, Weight-Maintenance. J Clin Endocrinol Metab 88: 3577–3583, 2003

Parker et al. Effect of a High-Protein, High–Monounsaturated Fat Weight Loss Diet on glycemic Control and Lipid Levels in Type 2 Diabetes. Diabetes Care 25:425–430, 2002.

Seppo, L., Jauhiainen, T., Poussa, T. & Korpela, R. () A fermented milk high in bioactive peptides has a blood pressure-lowering effect in hypertensive subjects. Am. J. Clin. Nutr. 2003; 77: 326–330.
Unger RH. Glucagon physiology and pathophysiology. N Engl J Med. 1971; 285:443– 449.

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About Protica Research

Founded in 2001, Protica Research (Protica, Inc.) is a nutritional research firm specializing in the development of capsulized foods (dense nutrition in compact liquid and food forms). Protica manufactures Profect (www.profect.com), IsoMetric, Pediagro, Fruitasia and more than 100 other brands in its GMP-certified, 250,000 square foot facility. One area of specialty is the manufacturing of Medicare-approved, whey liquid protein for diabetic patients.

You can learn more about Protica at www.protica.com - Copyright - Protica Research

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