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Protein Requirements in Hospitalized Patients



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By : Jim Duffy    99 or more times read
Submitted 2010-04-15 16:39:27
Nutritional status is usually impaired among hospitalized patients. It's widely agreed that routine hospital practices can further adversely have an impact on the nutritional status of sick patients. It's apparent the lack of protein has serious implications for health, recovery from illness or surgery, and hospital costs, and that meeting protein requirements is imperative. Several sick patients recuperating from sickness or injury also have a high protein necessity as various body tissues are composed of proteins.


Pathophysiology:

Protein energy malnutrition (PEM) happens often in hospitalized patients and is brought on by starvation. It is the disease that develops when protein intake or energy intake, or both, chronically fail to satisfy our body's requirements for these nutrients. The majority of humans possess adaptive mechanisms that slow down and a large amount of times will entirely arrest this common diseases progress. Fat storage is amplified due to the reduction in energy expenditure. Our body reduces its metabolic rate per unit of the metabolically active tissues and uses our body's lean tissue protein store to accomplish this. This protein-depleted body additionally needs less protein. Whereas the central lean tissues, like those of the liver, gastrointestinal tract, kidneys, blood and immune cells are spared, the mucle tissue must bear this loss. In your body's effort to promote homeostasis it will eventually adapt to the status it is in, so long as the defficiency doesn't drop to a point where it cannot perform in by doing this. This physiologic adaptation ends up in lowered metabolic rate and additionally reduces the muscle mass. The consequences of this include muscular weakness, functional disability, reduced cardiac and respiratory capability and a reduced body protein reserve.


A few of the variables that help preserve a hospitalized patient's nutritional standing incorporate:

1. Checking the patient's weight (on admission and a minimum of once each day throughout treatment)

2. Keeping track of the daily diet (varieties of food, amounts, by what feeding technique, etc.)

3. Assigning one to 1 patient care (one nurse per shift should be responsible for the patient and encourage intake)

4. When providing prolonged administration of dextrose and electrolyte-containing solutions, protein supplements should additionally be provided to forestall dehydration and malnutrition.

5. The patient should be supplied nutritional and protein supplements prior to the metabolism triggering a negative nitrogen balance.

6. Patients normally do not eat well within the hospital because of mental and organic stress. Focused sources of nutrition and proteins can guarantee adequate intake in such situations.

7. It's critical to note that malnutrition needs to be addressed proactively. Failure to take action will result in grave health problems alone. Morbidity may be prevented by merely addressing one of its chief causes which can be malnutrition that leads to a depressed immune system, metabolic abnormalities and organ failures.


Remedies:

Hospitalized patients must be diagnosed with a protein necessity extremely promptly. In an endeavor to enhance the patient's outcome continual examinations will help achieve this. In reasonable to serious cases, even sufficient protein provision could build up immune function and muscle function as much as necessary to improve the patient’s situation. Mobilization and exercise are essential for nutritional rehabilitation.

- Oral nutrition is most secure, least costly, and usually thought to be the most effective remedy for malnutrition.

- When nutritional needs cannot be met through diet, forced feeding (orally, employing a syringe, tongue depressor, etc.) should be executed.

- When the gastro-intestinal system can not be used intravenous feeding through the gut is essential (often known as parenteral nutrition).

Hospitalized patients that have sustained a significant burn or trauma, or chronic conditions like diabetes, cancer, etc. need protein supplementation. Until these patients totally recover they'll continue to require extra protein. Thus, a higher protein diet is usually usually indicated.

Such hospitalized patients need just about 1.5 grams of protein per kilogram of body weight according to their weight, where ordinary adults require 0.8 grams of protein per kilogram. Meals offered at home or within the hospital could not supply enough protein to satisfy this requirement. Therefore, protein supplementation is mostly needed.

The routes through which these protein nutrients are provided incorporate tailored oral diet, interal nutrition by tube (i.e. providing nutrients to the gastrointestinal tract by tube), or parenteral nutrition. In the case of interal tube nutrition, the formulas satisfy the energy needs, however are oftentimes lacking in proteins.


The necessity for milk proteins as supplements in hospitalized patients:

Passive immunization through food is distinctive to mammals, and most of us receive this benefit at birth. Newborns are unable to create immunoglobulins. They receive this through the mother’s milk. Patients with particular illnesses need to be supplied with these types of proteins as some are similar to newborns in that they additionally are unable to construct their own immunoglobulins. Among these are casein and whey protein. These proteins are not only of biological origin but these additionally help to augment the usually-poor diet and have a vital impact on immune function.

Casein: The milk protein casein is considered the leading essential protein fraction of milk. The peptides in casein are able to impact gut motility, decrease gut emptying and stimulate immune modulator activity. Additionally, casein ingestion has an vital effect to preserve activity and aid in absorption of different biologically active peptides.

Whey: Whey is a byproduct of cheese and casein manufacture. Twenty percent of the initial milk proteins are contained in whey. After acidification or partial digestion is when these proteins become biologically active. Biological activities consist of immune modulation, as well as anti-inflammatory and healing effects. It has additionally been proven that whey is constructive in patients with chemical-induced corrosive injury.

Therefore milk proteins like whey and casein should be considered to battle the protein deficiency of some hospitalized patients.

Hospitalized patients require an understanding of amino acids and protein requirements under special clinical conditions. Improvement of information in this area and prompt diagnosis will assist hospitalized patients with their specific protein requirements and thus will aid in medical care.


References

1. Klein S. “Nutritional Therapy”. In: Ahya S, Flood K, Paranjothi S (eds). The Washington Manual of Medical Therapeutics. 30th ed. Philadelphia: Lipincott Williams & Wilkins. 2000: 27-42.

2. Blackburn G.L., Bistrian B.R. “Protein Calorie Curative Therapy in Nutritional Support of Medical Practice”. H. Schneider (Edit). Harper & Row, 1976.

3. Blackburn G. L.: (1978). “Criteria for Evaluation of Protein Quality in Patients”, report presented at American Society for Parenteral and Enteral Nutritional Jul, Boston; and American Dietetic Association, Sep, San Antonio.

4. Detsky A.S., Smalley P.S., Chang J. Is this patient malnourished? JAMA 1994; 271:54-8.

5. Hoffer L.J. “Clinical nutrition: 1. Protein–energy malnutrition in the inpatient”. CMAJ. November 13, 2001; 165 (10).

6. Sullivan D.H., Sun S., Walls R.C. “Protein-energy undernutrition among elderly hospitalized patients: a prospective study”. JAMA 1999; 281:2013-9.

7. Heyland D.K., MacDonald S., Keefe L., Drover J.W. “Total parenteral nutrition in the critically ill patient: a meta-analysis”. JAMA 1998; 280:2013-9.

8. Corish C.A., Kennedy N.P. “Protein–energy undernutrition in hospital in-patients”. British Journal of Nutrition. June 2000, vol. 83, no. 6, pp. 575-591(17).

9. Dennis H.S., Sun S., Robert C.W. “Protein-Energy Undernutrition Among Elderly Hospitalized Patients”. JAMA. 1999; 281:2013-2019.

10. Anker S.D., Coats A.J. “Cardiac cachexia: a syndrome with impaired survival and immune and neuroendocrine activation”. Chest 1999; 115:836-47.

11. Ghosh S., Playford J.R. “Bioactive natural compounds for the treatment of gastrointestinal disorders”. Clinical science. 2003; 104: 547-556.

Author Resource:



About Protica Research

Founded in 2001, Protica Research (Protica, Inc.) is a nutritional research firm specializing in the development of capsulized foods (dense nutrition in compact liquid and food forms). Protica manufactures Profect (www.profect.com), IsoMetric, Pediagro, Fruitasia and more than 100 other brands in its GMP-certified, 250,000 square foot facility. One area of specialty is the manufacturing of Medicare-approved, whey protein drinks for cancer patients.

You can learn more about Protica at www.protica.com - Copyright - Protica Research

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