Hodgkin's disease may be a kind of cancer called a lymphoma , which could be a cancer of the lymphatic system. Hodgkin's includes a long and wealthy history. The disease was named after Thomas Hodgkin, a English scholar and Quaker physician operating at Guy's Hospital in England. Hodgkin's disease, typically referred to as Hodgkin's lymphoma, is a cancer that starts in lymphatic tissue. It's named once the British physician Thomas Hodgkin, who first described the disease in 1832 and noted several characteristics that distinguish it from other lymphomas. Hodgkin's lymphoma is characterized clinically by the orderly spread of disease from one lymph node group to another and by the event of systemic symptoms with advanced disease. Pathologically, the disease is characterized by the presence of Reed-Sternberg cells. In the United States, approximately 1,700 kids and adolescents younger than 20 are diagnosed with lymphomas each year. Hodgkin's disease enlarges the lymphatic tissue, which will then cause pressure on vital structures. It can spread through the lymphatic vessels to different lymph nodes. In Hodgkin's disease, cells in the lymphatic system become abnormal. They divide too rapidly and grow while not any order or control. Because lymphatic tissue is present in several elements of the body, Hodgkin's disease will start almost anywhere.
Hodgkin's lymphoma was one of the first cancers to be rendered curable by combination chemotherapy. The lymph nodes are oval, pea-sized organs. They're found beneath the skin along the route of large blood vessels, and they are grouped in areas like the neck, underarms, groin, abdomen (trunk), and pelvis (hips). Hodgkin's disease could occur during a single lymph node, a group of lymph nodes, or, typically, in alternative components of the lymphatic system such as the bone marrow and spleen. This type of cancer tends to unfold in an exceedingly fairly orderly method from one group of lymph nodes to the next group. As a result of lymphatic tissue is present in several elements of the body, Hodgkin's disease can begin virtually anywhere, but most usually starts in lymph nodes in the upper half of the body. The foremost common sites are within the chest, neck, or underneath the arms. It's one of two common varieties of cancers of the lymphatic system. Non-Hodgkin's lymphoma, the opposite sort, is far additional common. In the United States in 2004, there have been concerning 7,880 new cases of Hodgkin's disease, compared with fifty four,320 new cases of non-Hodgkin's lymphoma.Hodgkin's disease is rare in children beneath five years of age. In youngsters below age 10, it's more common in boys than girls.
Causes of Hodgkin's disease
The common causes and risk issue's of Hodgkin's disease include the subsequent:
The precise explanation for Hodgkin's lymphoma is unknown.
Individuals who have had Epstein-Barr virus, that will cause infectious mononucleosis (mono), might be at a slightly higher risk for Hodgkin's.
Several factors- such as age and genetics - are most likely beyond our control.
Environmental or lifestyle-related variables.
Family members of patients who carry the disease.
It's more common in men than in women.
Symptoms of Hodgkin's disease
Some sign and symptoms connected to Hodgkin's disease are as follows:
Fever and chills.
Night sweats.
Painless swelling of lymph nodes in your neck, armpits or groin.
Children who have Hodgkin's disease generally suppose they need the flu. They'll have fevers, feel achy, or have swollen glands, that feel and appear like bumps, usually in the neck or groin area.
Itchiness on the trunk of the body.
Uncommon back or abdominal pain.
Fatigue.
Unexplained weight loss.
Shortness of breath.
Treatment of Hodgkin's disease
Here is list of the ways for treating Hodgkin's disease:
When the disease is confined to a restricted area, radiation therapy is that the treatment of choice.
Stem cell transplantation- to enable treatment with high doses of chemotherapy.
Biological therapies- that use naturally occurring substances of the immune system to prevent lymphoma progression.
Bone marrow transplant.
For patients with clinical stage IA disease that's nonbulky and involves the mediastinum with NS histology, mantle irradiation alone could be adequate therapy.
Combined modality therapy, that is chemotherapy for 4-vi cycles followed by involved-field radiotherapy, is used.
The foremost commonly used regimen is termed ABVD and is comprised of 4 chemotherapy agents. These drugs are given intravenously (in the vein) each 14 days, often up to twelve times.
Author Resource:
Carey Howard has been writing articles online for nearly 2 years now. Not only does this author specialize in Diseases, you can also check out his latest website about:
![[Valid RSS feed]](http://www.look4articles.com/images/icon_Rss.png "XML Feed For RSS"){kind=icon}
Category Rss Feed
Print This Article
Add To Favorites
![[Valid RSS feed]](http://www.look4articles.com/images/rss.jpg "XML Feed For RSS")