The Resveratrol craze is taking the world by storm. With international media coverage, more and more people are learning about Resveratrol and the wonderful benefits of taking it. Resveratrol (trans resveratrol) is a phytoalexin that is produced naturally by various plants. Plants produce Resveratrol as a natural response to attack by pathogens like fungi and bacteria. It is also produced by chemical synthesis.
Resveratrol was first isolated by Takaoka in the roots of white hellebore back in 1940. It was found again in 1963 from the roots of the Japanese knotweed plant. However, it attracted world wide attention in 1992 when a researcher found its presence in wine. After this milestone discovery it was suggested as the explanation for the cardiovascular benefits of red wine.
Taking Resveratrol has various cardiovascular benefits. Its been found to lower blood sugar and has anti inflammatory properties as well as anti cancer effects. In 1997, Jang reported that topical Resveratrol applications prevented skin cancer development. The strongest evidence of the anti cancer action of Resveratrol exists for tumors it comes into direct contact with, such as skin and gastrointestinal tract tumors. In 2003, the groups of Howitz and Sinclair reported in the journal Nature that Resveratrol extends the lifespan.
Scientists in Italy derived the first positive result of Resveratrol supplementation in a vertebrate in 2006. Using a short lived fish, with an average life span of about nine weeks, the scientists found that a dose of Resveratrol increased the median lifespan of the fish by a whopping 56 !
Resveratrol comes from various plant sources such as vines, peanuts, Japanese Knotweed and the skin of red grapes. It is a constituent of red wine, and has been used to explain the French Paradox. In grapes, Resveratrol is found mainly in the skin, and in muscadine grapes it’s found in the seeds as well. Red wine contains between 0.2 and 5.8 mg/L of Resveratrol depending on the grape variety. White wine generally contains much less than red. The reason is that red wine is fermented with the grape skins, allowing the wine to absorb the resveratrol, whereas white wine is fermented after the grape skin has been removed.
The dynamics of Resveratrol s effects on life extension are not yet fully understood, but appear to mimic several of the physiological effects of calorie restriction. Calorie restriction causes a natural reaction in the body that boosts metabolism, makes blood flow better, fat burn more efficient, and over all health improve. Reports indicate that Resveratrol activates the Sirtuin 1 (SIRT1) and PGC 1& #945; genes and improves the functioning of the mitochondria.
As ever more research is being done on Resveratrol, scientists are finding more and more uses for this beneficial natural supplement. It has been featured on Dr. Oz and Oprah, Fox News, CNN, CBS, ABC and other major media outlets. The Resveratrol craze is taking the world by storm and rightfully so. It’s proving to be a major asset to various needed health improvements. Researchers have called it “The most profound discovery in medical science since antibiotics”.
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