Swelling (inflammation) will be the body's natural reaction to an injury. Inflammation can happen anywhere on the skin, inside the body, as well as inside the arteries. Scientists are now learning inflammation may perhaps play a part in lots of of the diseases that come with aging, including coronary artery illness.
For numerous years, doctors have thought that the primary cause of a heart attack or stroke or was the buildup of fatty plaque inside an artery, leading to the heart or brain. In time, the plaque buildup would narrow the artery so a lot, that the artery would close off or develop into clogged by a blood clot. The lack of oxygen-rich blood to the heart would then lead to a heart attack. On the other hand these sorts of blockages trigger only about 3 out of 10 heart attacks.
Researchers are finding folks who that heart attacks don't have arteries severely narrowed by plaque! Vulnerable plaque could be buried inside the artery wall, and not bulge out and block the blood flow through the artery. This is why researchers began to take a look at how inflammation affects the arteries, and to see if inflammation could lead to a heart attack.
What they discovered was that inflammation leads to the development of "soft" or vulnerable plaque. They also discovered that vulnerable plaque was a lot more than just debris, clogging an artery, that it was filled with unique cell types that support with blood clotting.
When this inflammation is combined with other stresses, like high blood pressure, it can trigger the thin covering over the plaque to crack and bleed, spilling the entire contents of the vulnerable plaque into the bloodstream. The sticky cytokines on the artery wall capture blood cells (primarily platelets) that rush to the internet site of injury. When these cells clump together, they are able to form a clot significant enough to block the artery
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